Taxol Drug Resistance Cell Lines In Breast Cancer
gene expression analyzed data for Paclitaxel drug resistance in breast cancer
@kaggle.aliabedimadiseh_taxol_drug_resistance_cell_lines_in_br_918b4375
About this Dataset
Taxol Drug Resistance Cell Lines In Breast Cancer
This dataset collected from NCBI - GEO datasets:
- GSE144113 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE144113)
- GSE76200 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE76200)
- GSE12791 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE12791)
These datasets include four paclitaxel-resistant cell lines which includes BAS, HS578T, MCF7 and MDA-MB-231.
Gene expression analysis was performed using R in each of the datasets, which was between control cells and drug-resistant cells. And using different Bioinformatics databases, they were converted into gene symbols. Genes with a p-value of less than 0.05 were also removed.